Application of Sulfonic Acid Functionalized Nanoporous Silica (SBA-Pr-SO3H) in the Green One-pot Synthesis of Polyhydroacridine Libraries
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Abstract:
1,8-Dioxo-decahydroacridines have been synthesized by the three-component reaction of aromatic aldehydes, aromatic amines (or ammonium acetate), and dimedone in the presence of sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) under solvent-free conditions. Excellent yields, short reaction times, mild reaction conditions, and easy work-up procedures are advantages of this green method.
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Journal title
volume 32 issue 4
pages 9- 16
publication date 2013-12-01
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